Megalis 10 Mg (Tadalafil)

Megalis 10mg is a PDE type5 inhibitor class action of medicine which is manufactured by Macleods Pharmaceuticals Pvt Ltd. The active pharmaceutical ingredient present inside the medicine is Tadalafil which is used by males with erectile dysfunction. The medicine is going to suppress the symptoms of ED and induce a harder erection.


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What is Megalis 10mg?

Megalis 10mg is a PDE type5 inhibitor class action of medicine which is manufactured by Macleods Pharmaceuticals Pvt Ltd. The active pharmaceutical ingredient present inside the medicine is Tadalafil which is used by males with erectile dysfunction. The medicine is going to suppress the symptoms of ED and induce a harder erection.

Megalis, a 10 mg tablet, is manufactured by Macleods Pharmaceutical Pvt Ltd, a renowned pharmaceutical company certified globally. Megalis-10 comes in a pack of 4 tablets, and each tablet comprises 10 mg of the active therapeutic agent, tadalafil.

Tadalafil is an FDA-certified drug sold on a genuine prescription of a Urologist, Psychiatrist, Venereologist or Endocrinologist only. This medicine is a panacea in treating erectile dysfunction and other erection-related problems. To know more about this medicine, like its use, side effects, results, and working, read this blog ahead.

Megalis 10mg quick information
Active Ingredient: Tadalafil
Prescription Required? Yes, Prescription Is compulsory.
FDA Pregnancy Category: Category B
Habit Forming: Not habit-forming
Chemical Class: Carboline Derivative
Action Class: PDE-5 inhibitors
Sleepiness: Does not cause sleepiness
Schedule: Schedule H Medicine
Expires on or after: May, 2024

Mechanism of action of Tadalafil Drug

Tadalafil is the critical constituent of Megalis 10 mg tablet. It acts by inhibiting the activity of an enzyme known as phosphodiesterase-5 (PDE-5) which is responsible for the contraction of the smooth muscles and lowering the blood flow in the abdominal region, mainly the penis.

Hence, it helps in relaxing the smooth muscles in the penile region and also enhances the flow of blood in the abdominal area. The overall activity results in the erection of the penis and boosted libido with high sexual time.

Megalis 10 mg details

Uses of Megalis 10 mg

  • It is mainly used to eliminate sex-related problems such as erection problems, short ejaculation time, impotence and poor libido.
  • This medicine is also employed in the management of benign prostate enlargement.
  • Other than sex-related issues, this medicine can be recommended to manage hypertension as it relaxes the walls of blood vessels and increases blood flow.

Side Effects of Megalis 10 mg

Educate yourself about possible side effects that may arise, such as: headaches, flushing, or upset stomach, so you are prepared to address them if they occur.

Potential Side Effects of Megalis 10 mg Requiring Immediate Attention:

If you are taking Megalis 10 mg medicine and experience any of the following symptoms, it’s crucial to stop the medication and seek immediate medical assistance:

  1. Allergic Reactions: Look out for signs such as rash, swelling, or breathing difficulties.
  2. Priapism: This condition involves a painful and prolonged erection.
  3. Swelling of Extremities
  4. Chest Pain and Cardiovascular Issues
  5. Sudden Vision/Hearing Loss
  6. Severe Hypotension: This indicates an abnormally low blood pressure.
  7. Shortness of Breath
  8. Severe Headache and Nausea

Megalis 10 mg: Common and Less Severe Side Effects

While the following side effects are typically less severe, it is advisable to consult with a healthcare provider to address them effectively. These common side effects may include:

  • – Dizziness or lightheadedness
  • – Flu-like symptoms
  • – Back pain
  • – Flushing, which can manifest as a feeling of warmth or redness in the face, neck, or chest
  • – Muscle pain, often referred to as myalgia
  • – Mild stomach discomfort or indigestion
  • – Mild to moderate headache
  • – Stuffy or runny nose
  • – Minor changes in vision, such as blurred vision or a blue-green tinge to objects

Ensuring Your Safety When Using Megalis 10 mg

  1. Consult a Healthcare Professional: Before embarking on an ED medication regimen, it is crucial to consult a healthcare professional for personalized guidance. Be sure to disclose your medical history and any concerns you may have.
  2. Prescribed Medications Only: Always obtain ED medications with a valid prescription from a qualified healthcare provider. Avoid purchasing them from unauthorized sources.
  3. Follow Dosage Instructions: To minimize the risk of side effects and potential health risks, strictly adhere to the recommended dosage instructions provided by your healthcare provider.
  4. Understand Potential Side Effects: Educate yourself about possible side effects that may arise, such as headaches, flushing, or upset stomach, so you are prepared to address them if they occur.
  5. Be Aware of Drug Interactions: Make sure to inform your healthcare provider about all medications you are currently taking, both prescription and over-the-counter, to prevent any potentially dangerous drug interactions.
  6. Monitor for Allergic Reactions: If you experience any allergic symptoms, seek immediate medical assistance.
  7. Do Not Mix with Nitrates: mixing these medicines can lead to severe health risks.
  8. Keep Medication Secure: Store this medicine in a secure place, out of the reach of children, and never share it with others.


Following are Various interactions that can occur when Megalis 10 mg is combined with different drugs and substances.

  1. Nitrates: Nitrates are medications commonly prescribed to prevent chest pain(angina). When combined with Megalis 10 mg, a severe drop in BP(blood pressure) may occur, leading to dizziness.
    Examples of common nitrates that interact with Megalis 10 mg are provided below.
  • Nitro-Dur (Nitroglycerin)
  • Isosorbide dinitrate (Isordil )
  • Isosorbide mononitrate
  • poppers
  1. Protease Inhibitors: Protease inhibitors, commonly used for viral infections such as HCV and human immunodeficiency virus, can increase the risk of side effects when combined with Megalis 10 mg.
    Examples of common protease Inhibitors that interact with Megalis 10 mg are provided below.
  • Atazanavir
  • Invirase
  • Viracept (Nelfinavir)
  • Norvir
  • Indinavir (Crixivan)
  1. Alpha Blockers: Alpha blockers are commonly employed to regulate high blood pressure (BP). When taken concurrently with Megalis 10 mg, these medications work in tandem to further decrease BP by inducing muscle relaxation. The result of this combined approach is a noteworthy reduction in blood pressure.
    Examples of common alpha blockers that interact with Megalis 10 mg are provided below.
  • Cardura 
  • Minipress (Prazosin)
  • Flomax (Tamsulosin)
  • Uroxatral
  1. Anti-Infective Medications: Similar to protease inhibitors, certain anti-infective medications can interact with Megalis 10 mg, potentially amplifying side effects.
  2. Alcohol: Alcohol, like Megalis 10 mg, can relax blood vessels, leading to a drop in blood pressure.
  3. Grapefruit: Grapefruit and grapefruit juice can interfere with the metabolism of Megalis 10 mg, leading to an increase in its concentration in the body.

Quick tips to keep in mind

  • Megalis, a 10 mg tablet, will make you sexually excited after 20-30 minutes of taking the medicine. Do not consume more than the prescribed medicine with the thought of getting the result faster and unlikely you will get the adverse effect faster.
  • Consume the tablet with plenty of water without chewing or breaking the pill.
  • You should take medicine on an empty stomach or after 4-6 hours of a meal. It will get absorbed, reach the circulatory system better, and the erection will be phenomenal.
  • You should consult a doctor before consuming the medicine. A doctor will guide you regarding the dose and frequency to achieve an effective outcome.
  • If you are suffering from heart, liver or kidney problems, do not consume the medicine or consult the doctor.
  • Do not combine the Megalis tablet with other medications, such as alpha-blockers or nitrates, as the medicine will work synergically and drop the blood pressure to a remarkable level, causing fainting, hallucination, and even a heart attack.
  • Do not drive any vehicle, if possible, as you might feel dizzy or sleepy after consuming the medicine.
  • You should not consume any narcotic product, tobacco, or alcohol while following the regimen of tadalafil medicine. The combination will affect the absorption of the drug, and you might not get the desired result of proper erection and high libido, although it will make you feel dizzy.
  • Avoid storing the medicine in a sunny or damp place, as such storage conditions will affect the pharmaceutical attributes of the tablet. It will also decrease the shelf life of an active therapeutic agent.
  • Tadalafil drug is not for children, so keep it out of the reach of children.

Most asked questions

  • Does Megalis 10 mg tablet affect fertility?

No, the consumption of Megalis tablets will not exert any effect on fertility. It enhances the blood flow in the penile blood vessel and relaxes muscles to produce an erection.

  • When to stop consuming tadalafil medicine?

Suppose you feel uneasiness while or after consuming the medication or face any skin-related issues or irritation in the stomach. In that case, you must stop the intake and consult your doctor as soon as possible.

  • What are the common tolerable side effects of this medicine?

Most of the side effects of tadalafil tablets are tolerable and do not last longer than 3-5 hours. The common side effects are-

    • Headache
    • Altered vision
    • Rashes
    • Dyspepsia
    • Body pain
    • Flushing- a sense of warmness on the face and limbs
  • What are the benefits of Megalis 10 mg tablet other than solving erection problems?

Megalis tablet is majorly used in the betterment of erectile function. However, it could be helpful in treating pulmonary hypertension as vasodilation is the effect of tadalafil, which will reduce the blood pressure to relieving the patient. It is also used to treat benign prostate hypertrophy (BPH).

  • Which type of food should be taken and avoided while following the tadalafil medicine regimen?

Diet plays a vital role in deciding the ADME parameters for the drug. As per FDA’s advice, medication should be taken in a fast state or 4-6 hours before or after consuming the food. Alcohol is most commonly consumed by people, which reduces the absorption of the drug. Grapes should not be consumed as they will hinder the absorption of the drug by suppressing the intestinal receptors. However, you can take dark chocolate and coffee before or after consuming the medicine. It will enhance the working and give a better erection.

  • Is it safe to take one tablet daily?

Yes, it is entirely safe to consume one Megalis 10 mg tablet daily at the scheduled time, as mentioned in the medicine box, or a doctor prescribes it. To get the best result, consume the medicine 20-30 minutes before sexual activities.

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 Tadaflo 10 mg   | Tastylia 10 mg   |  zenegra 50  |  Vigore Oral Jelly  |  

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  • Medzpills aims to provide visitors with reliable, trustworthy, and expert-reviewed information. This article has been reviewed by Parry Stone, an expert in the field. However, it is important to note that the information presented should not be used as a substitute for the advice of a qualified medical professional. The information provided serves only as a source of knowledge and may not cover all aspects of health conditions, lab tests, medications, potential side effects, drug interactions, warnings, alerts, and more. It is highly recommended to consult with your doctor and address any concerns or questions you may have about a specific disease or medication. At Medzpills, we strive to supplement, rather than replace, the essential doctor-patient relationship.


Active Ingredient


Delivery Time:

6 To 15 days


Erectile Dysfunction


Macleods Pharmaceuticals Pvt. Ltd.


4 Tablets in 1 strip



Equivalent Brand


Pharmaceutical Form


Country of origin



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