Penegra 25 mg (Sildenafil Citrate)

Penegra 25mg is a PDE type5 inhibitor class action of medicine, and the aim of consuming it is male sexual wellness. The active pharmaceutical ingredient inside the medicine is Sildenafil Citrate, which helps males suffering from erectile dysfunction.


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What is Penegra 25 mg?

Penegra 25 mg is a PDE type5 inhibitor class action of medicine, and the aim of consuming it is male sexual wellness. The active pharmaceutical ingredient inside the medicine is Sildenafil Citrate, which helps males suffering from erectile dysfunction. It is a condition in which a male cannot gain a harder erection while having intercourse, and its intensity decreases with every passing day. Due to this symptom of ED, the male and their female partner notice a major decline in libido and sexual satisfaction levels.

The medicine helps temporarily improve issues by providing a window to patients to have satisfactory intercourse. The medicine manufacturer is Zydus Cadila, which packs the medicine in a strip of 4 tablets. Each tablet is pink oval, consisting of 25 mg of Sildenafil Citrate. The medicine requires a prescription to get it; a person must visit the physician and discuss the issue in complete detail.

Uses of Penegra 25 mg

  • Patients of erectile dysfunction can take help from the Penegra 25mg medicine. It is one of the best temporary solutions for the issue until it is permanently improved.
  • People with Pulmonary Arterial Hypertension issues can also get a prescription for the medicine. It is a situation in which a person’s blood pressure increases and causes major symptoms in the body.

Benefits of using Penegra 25 mg

  • People consuming the medicine will enjoy the benefit of a harder erection.
  • Increased libido and sexual satisfaction levels are also the benefits of using the medicine.
  • Normal blood pressure is also a benefit of consuming Penegra 25mg medicine.

How does Penegra 25 mg work?

To understand how the medicine works, it is important to understand that it will only help in erectile dysfunction cases caused by PDE type5. It is a hormone released by the body when the heart of a male is under some kind of risk. Now, due to various human activities like not performing enough physical activity, consuming only junk food, living a life full of depression and stress, etc. In these cases, the heart is at risk, and PDE type5 is released, which enters the blood vessels.

Here, it is going to attach and stop the release of cGMP, which is a vasodilator. Soon, the blood vessels contract and blood is unable to reach the penis in adequate amounts leading to a softer erection and erectile dysfunction. When a male consumes the medicine, Sildenafil citrate dissolves in the body and enters the blood vessels. It will avert all the actions taken by PDE type5, leading to a release of cGMP. It will start dilating the blood vessels again, which helps in gaining a harder erection when a person is sexually aroused.

Dosage Requirements

The dose of Penegra 25 mg medicine that one requires to get the best erection is decided by the physician. They are going to check the erectile dysfunction levels in the patient’s body and medicine/ disease interactions. First of all, they ensure whether a person is safe to use the medicine or not through interactions. After that, the physician moves to check the issue levels based on which they prescribe the dose. It is generally one or two per day.


For detailed information on the interactions of Penegra 25 mg with drugs, alcohol, supplements, food, and diseases, please visit the Sildenafil Interaction page.

Penegra 25 mg and Alcohol/Supplements/Food Interactions

  • Alcohol (Ethanol)  and Penegra 25 mg 

    • Increased risk of heart problems
    •  Reduced effectiveness of Penegra 25 mg
    • Increased risk of side effects
  • Penegra 25 mg  and Supplements/foods Interactions

    • Yohimbine: Drop in blood pressure.
    • L-arginine: Dangerous drop in blood pressure
    • Grapefruit juice: It Can lead to a higher risk of side effects

Penegra 25 mg drug interactions

  • Major drug interactions

    • Delavirdine (Rescriptor)
    • Adagrasib
    • Nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Minitran, Nitro-Bid, Rectiv, GoNitro)
    • Nefazodone (Serzone)
    • Ketoconazole (Nizoral)
    • Isosorbide (Isordil, Dilatrate-SR)
    • Darunavir (Prezista)
    • Amprenavir (Agenerase)
    • Cobicistat (Tybost)
    • Nitroprusside (Nitropress)
    • Atazanavir (Reyataz)
    • Fosamprenavir (Lexiva)
    • Levoketoconazole
    • Amyl Nitrite
    • Avanafil (Stendra)
  • Moderate drug interactions

    • Allopurinol
    • Gabapentin
    • Lisinopril
    • Levothyroxine
    • Losartan
    • Carvedilol
    • Pantoprazole
    • Amlodipine
    • Fluoxetine
    • Warfarin
    • Citalopram
    • Metformin
    • Metoprolol

Penegra 25 mg disease interactions

  • Disease Interactions that are of high clinical significance.

    • pulmonary veno-occlusive disease (PVOD): Worsening symptomsof PVOD and potentially life-threatening complications.
    • Cardiovascular Disease: May experience a significant drop in blood pressure
    • Renal dysfunction: may result in drug accumulation.
  • Disease Interactions that are of less clinical significance.

    • Priapism
    • Alcoholism
    • Hearing Loss
    • Liver Disease
    • Retinitis Pigmentosa
    • Seizure Disorders

Side Effects

If you experience any side effects from Penegra 25 mg, please contact your healthcare provider immediately. You can refer to the comprehensive list of side effects associated with medications containing sildenafil: Full List of Side Effects for Medications Containing Sildenafil.

The below side effects demand immediate medical attention.

  • Uncommon side effects:

    • Prickling, tingling, or numbness sensations.
    • Tenderness in the stomach area.
    • Nausea.
    • A feeling of burning or discomfort in the chest or abdomen.
    • More frequent need to urinate.
    • Burning or aching in the bladder.
    • Painful urination.
    • Lightheadedness.
    • Urine that is cloudy or bloody.
    • Priapism (painful erections)
  • Rare side effects:

    • Breast enlargement.
    • Fever or chills.
    • Difficulty focusing.
    • Confusion.
    • Unusual sensation of burning or stinging on the skin.
    • Aching in the lower back or side.
    • Blurred vision.
    • Twitching of the muscles.
    • Chest pains.
    • Seizures.
    • Severe or persistent headache.

Less severe side effects of Penegra 25 mg

  • Side effects frequently observed:

    • Diarrhea.
    • Sneezing.
    • Insomnia.
    • Muscular aches and pains.
    • Headaches.
    • Flushing.
    • Nasal congestion or runny nose.
    • Nasal bleeding.
  • Infrequent side effects:

    • Diarrhea or cramps (severe or ongoing).
    • Enlargement of the face, hands, feet, or lower legs.
    • Coughing.
    • Swallowing difficulty.
    • Paleness of the skin.
    • Unpleasant sexual effects in men (persistent), such as the inability to experience an orgasm.
    • Ulcers in the mouth or on the lips.
    • Poor coordination.
    • Asthma worsening.
    • Vomiting.

Related Products


  • Sildenafil: MedlinePlus Drug Information. Available online: Reference Link
  • Sildenafil Interactions: Available online: Reference Link
  • Sildenafil (Oral Route) Side Effects: Available online: Reference Link
  • Definition & Facts for Erectile Dysfunction: Available online: Reference Link


The content presented on this page is intended solely for general informational purposes and must not be viewed as a replacement for expert medical advice, diagnosis, or treatment. It is imperative to consult with a certified healthcare professional for guidance on any medical condition, symptom, or inquiry. Never ignore or postpone seeking professional medical advice based on information obtained from this page.

Active Ingredient

Sildenafil Citrate


Zydus Cadila, India


Erectile Dysfunction


4 Tablets in 1 strip


25 mg

Delivery Time:

7 to 15 days


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