With Sildenafil citrate as its active ingredient, each strip contains 10 tablets, each with 25 mg of the pharmaceutical component. Manufactured by RSM Enterprises.


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What is Sildigra 25 mg?

Sildigra 25 mg is a mild allopathic solution for early-stage erectile dysfunction in men. It aims to alleviate entry-level challenges, such as difficulty achieving desired hardness during sexual activity.

With Sildenafil citrate as its active ingredient, each strip contains 10 tablets, each with 25 mg of the pharmaceutical component. Manufactured by RSM Enterprises.


Sildigra 25 mg quick information
Active Ingredient: Sildenafil
Prescription Required? Yes, Prescription Is compulsory.
FDA Pregnancy Category: Category B
Habit Forming: Not habit-forming
Chemical Class: Benzene sulfonamide Derivative
Action Class: PDE-5 inhibitors
Sleepiness: May cause sleepiness
Schedule: Schedule H Medicine
Expires on or after: May, 2025

Uses of Sildigra 25 mg

  • Erectile dysfunction is the main reason why the physicians prescribe this medicine to the males.
  • Pulmonary Arterial Hypertension (PAH): In addition to treating ED, sildenafil is also used to manage Pulmonary PAH (Arterial Hypertension).

How does Sildigra 25 mg work?

To completely understand how the Sildigra 25 mg medicine works, it is important to understand how the issue happens in the first place. Because of various bad habits adopted by humans, like consuming only junk food, not performing any physical activity, living a stressed life, etc., the heart is at risk. To avoid this risk from increasing, the body releases the PDE-type5 hormone, which enters the blood vessels and attaches there. It will act on a vasodilator, cGMP, and block its release, leading to the contraction of blood vessels.

The blood is unable to travel to the penis when sexually aroused, leading to erectile dysfunction. When a person consumes the medicine, Sildenafil dissolves inside the blood vessels and finds PDE type5. Soon, Sildenafil blocks all its action, leading to increased cGMP levels. It will help dilate blood vessels, which helps more blood reach the penis when sexually aroused. It induces a harder erection, which is important for satisfactory intercourse.

Dosage Requirements

The physician decides the dose of medicine, which is generally one or two per day. The physician makes the decision of the dose based on the levels of issues that a person has and their medical history. This information will also help them ensure whether a male is safe to consume the medicine or not.


For detailed information on the interactions of Sildenafil with drugs, alcohol, supplements, food, and diseases, please visit the Sildenafil Interaction page.

Alcohol/Supplements/Food Interactions

  • Alcohol (Ethanol)  and Sildigra 25 mg

    • Increased risk of heart problems
    •  Reduced effectiveness of Sildigra 25 mg
    • Increased risk of side effects
  • Sildigra 25 mg and Supplements/foods Interactions

    • Yohimbine: Drop in blood pressure.
    • L-arginine: Dangerous drop in blood pressure
    • Grapefruit juice: It Can lead to a higher risk of side effects

Sildigra 25 mg drug interactions

  • Major drug interactions

    •  Isosorbide (Isordil, Dilatrate-SR)
    • Riociguat (Adempas)
    • Nelfinavir (Viracept)
    • Ceritinib (Zykadia)
    • Ketoconazole (Nizoral)
    • Delavirdine (Rescriptor)
    • Ritonavir (Norvir)
    • Amprenavir (Agenerase)
    • Lonafarnib (Zokinvy)
    • Levoketoconazole
    • Adagrasib
    • Itraconazole (Sporanox)
    • Nitroprusside (Nitropress)
    • Avanafil (Stendra)
    • Nefazodone (Serzone)
  • Moderate drug interactions

    • Metformin
    • Carvedilol
    • Levothyroxine
    • Allopurinol
    • Warfarin
    • Furosemide
    • Pantoprazole
    • Lisinopril
    • Hydrochlorothiazide
    • Amlodipine
    • Fluoxetine
    • Atorvastatin
    • Losartan

Sildigra 25 mg disease interactions

  • Disease Interactions that are of high clinical significance.

    • pulmonary veno-occlusive disease (PVOD): Worsening symptomsof PVOD and potentially life-threatening complications.
    • Cardiovascular Disease: May experience a significant drop in blood pressure
    • Renal dysfunction: may result in drug accumulation.
  • Disease Interactions that are of less clinical significance.

    • Priapism
    • Alcoholism
    • Hearing Loss
    • Liver Disease
    • Retinitis Pigmentosa
    • Seizure Disorders

Side Effects

If you experience any side effects from Sildigra 25 mg, please contact your healthcare provider immediately. You can refer to the comprehensive list of side effects associated with medications containing sildenafil: Full List of Side Effects for Medications Containing Sildenafil. The side effects mentioned below should be addressed immediately by a medical professional.
  • Uncommon side effects:

    • Painful urination.
    • A feeling of burning or discomfort in the chest or abdomen.
    • Priapism (painful erections)
    • Burning or aching in the bladder.
    • Tenderness in the stomach area.
    • Lightheadedness.
    • Urine that is cloudy or bloody.
    • More frequent need to urinate.
    • Nausea.
    • Prickling, tingling, or numbness sensations.
  • Rare side effects:

    • Difficulty focusing.
    • Unusual sensation of burning or stinging on the skin.
    • Heightened thirst.
    • Blurred vision.
    • Stress or nervousness.
    • Confusion.
    • Twitching of the muscles.
    • Sensitivity to light.
    • Similar behavior changes to that of intoxication.
    • Expansion of the pupil.
    • Severe or persistent headache.
    • Breast enlargement.

Less severe side effects of Sildigra 25 mg

  • Side effects frequently encountered:

    • Labored breathing.
    • Insomnia.
    • Diarrhea.
    • Flushing.
    • Sneezing.
    • Nasal bleeding.
    • Headaches.
    • Nasal congestion or runny nose.
    • Discomfort and tenderness around the eyes and cheekbones.
    • Muscular aches and pains.
  • Infrequent side effects:

    • Enlargement of the face, hands, feet, or lower legs.
    • Ulcers in the mouth or on the lips.
    • Vomiting.
    • Diarrhea or cramps (severe or ongoing).
    • Difficulty breathing.
    • Asthma worsening.
    • Paleness of the skin.
    • Unpleasant sexual effects in men (persistent), such as the inability to experience an orgasm.
    • Tinnitus.
    • Stomach pains.

Related Products


  • Sildenafil: MedlinePlus Drug Information. Available online: Reference Link
  • Sildenafil Interactions: Available online: Reference Link
  • Sildenafil (Oral Route) Side Effects: Available online: Reference Link
  • Definition & Facts for Erectile Dysfunction: Available online: Reference Link


MedzPills is dedicated to providing visitors with accurate and reliable health information. This article has been carefully reviewed by an expert, Parry Stone. However, it’s important to understand that this information is not a substitute for advice from a qualified medical professional. Our information is meant to be a helpful resource, but it might not cover every aspect of health conditions, lab tests, medications, potential side effects, drug interactions, warnings, or alerts. It’s strongly recommended that you consult your doctor for any specific questions or concerns about a particular illness or medication. At MedzPills, our goal is to complement, rather than replace, the important doctor-patient relationship.

Active Ingredient

Sildenafil Citrate


Erectile Dysfunction


RSM Enterprises


25 mg

Equivalent Brand



10 tablets in 1 strip

Delivery Time:

6 To 15 days


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