Sildigra 250 is a very strong PDE-type inhibitor class action of medicine that is helpful for patients with erectile dysfunction. It is a condition in which a male cannot gain a harder erection, leading to unsatisfactory intercourse.


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What is Sildigra 250?

Sildigra 250 is a very strong PDE-type inhibitor class action of medicine that is helpful for patients with erectile dysfunction. It is a condition in which a male cannot gain a harder erection, leading to unsatisfactory intercourse. This leads to two other major issues: a decline in sexual satisfaction and libido levels. The medicine mainly helps temporarily relieve these issues until erectile dysfunction improves permanently.

The Sildigra 250 medicine is a product of RSM Enterprises, which packs the medicine in a strip of 10 tablets. It is a dark blue and diamond tablet with an engraving of 250 on it, meaning that it consists of 250 mg of API, Sildenafil Citrate. This ingredient falls in the prescription-based medicine category, so you must contact your physician and discuss the issue in detail.

Sildigra 250 quick information
Active Ingredient: Sildenafil
Prescription Required? Yes, Prescription Is compulsory.
FDA Pregnancy Category: Category B
Habit Forming: Not habit-forming
Chemical Class: Benzene sulfonamide Derivative
Action Class: PDE-5 inhibitors
Sleepiness: May cause sleepiness
Schedule: Schedule H Medicine
Expires on or after: July, 2025

Uses of Sildigra 250

  • The first use of the Sildigra 250 medicine is for erectile dysfunction.
  • The second use of the medicine is Pulmonary Arterial Hypertension. In this issue, the blood pressure of a person increases abruptly.

Benefits of using Sildigra 250

  • Getting better control on the blood pressure is the benefit of this medicine.
  • Gaining a harder erection for intercourse is a benefit of this medicine.
  • An increase in libido and sexual satisfaction levels is also a benefit of this tablet.

How does Sildigra 250 work?

Sildigra 250 medicine’s main task is to suppress the PDE type5 to help a male gain a harder erection for intercourse. To understand how the medicine performs this task, a person must first understand how the issue happens because of the PDE type5. The body releases this hormone in various situations where a person’s heart is at immense risk. Such a situation arises commonly because of bad habits of a person like not eating healthy, not performing any physical exercise, living a stressful life, etc.

In this case, PDE type5 enters the blood vessels and stops the release of cGMP. Its task is to keep the blood vessels dilated, and a decline in their levels leads to the contraction of blood vessels. Soon, you will notice that blood cannot reach the penis when a person is sexually aroused, leading to erectile dysfunction. When a person consumes the medicine, the Sildenafil will enter the blood vessel and block the activities of PDE type5.

The cGMP levels will again rise in the body, and you will notice dilation of blood vessels. Soon, blood enters the penis in adequate amounts leading to a harder erection whenever a person is sexually aroused.

Dosage Requirements

The decision of the dose of Sildigra 250 medicine is taken by the physician that you visit to discuss your erectile dysfunction problem. To decide, the physician will consider two main factors. The first factor is the medical history of the patient, which they use to ensure whether a person is safe to use the medicine. If the patient is found to be the same, the physician considers the levels of erectile dysfunction. Based on the information, they prescribe the medicine dose, which is generally one per day, taken half an hour before intercourse.


For detailed information on the interactions of Sildenafil with drugs, alcohol, supplements, food, and diseases, please visit the Sildenafil Interaction page.

Sildigra 250 and Alcohol/Supplements/Food Interactions

  • Alcohol (Ethanol)  and Sildigra 250

    • Increased risk of heart problems
    •  Reduced effectiveness of Sildigra 250
    • Increased risk of side effects
  • Sildigra 250 and Supplements/foods Interactions

    • Yohimbine: Drop in blood pressure.
    • L-arginine: Dangerous drop in blood pressure
    • Grapefruit juice: It Can lead to a higher risk of side effects

Sildigra 250 drug interactions

  • Major drug interactions

    • Levoketoconazole
    • Nitroprusside (Nitropress)
    • Isosorbide (Isordil, Dilatrate-SR)
    • Cobicistat (Tybost)
    • Boceprevir (Victrelis)
    • Nefazodone (Serzone)
    • Itraconazole (Sporanox)
    • Nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Minitran, Nitro-Bid, Rectiv, GoNitro)
    • Fosamprenavir (Lexiva)
    • Riociguat (Adempas)
    • Indinavir (Crixivan)
    • Clarithromycin (Biaxin)
    • Idelalisib (Zydelig)
    • Amprenavir (Agenerase)
    • Amyl Nitrite
  • Moderate drug interactions

    • Fluoxetine
    • Pantoprazole
    • Furosemide
    • Omeprazole
    • Allopurinol
    • Amlodipine
    • Atorvastatin
    • Hydrochlorothiazide
    • Metformin
    • Carvedilol
    • Simvastatin
    • Levothyroxine
    • Gabapentin

Sildigra 250 disease interactions

  • Disease Interactions that are of high clinical significance.

    • pulmonary veno-occlusive disease (PVOD): Worsening symptomsof PVOD and potentially life-threatening complications.
    • Cardiovascular Disease: May experience a significant drop in blood pressure
    • Renal dysfunction: may result in drug accumulation.
  • Disease Interactions that are of less clinical significance.

    • Priapism
    • Alcoholism
    • Hearing Loss
    • Liver Disease
    • Retinitis Pigmentosa
    • Seizure Disorders

Side Effects

If you experience any side effects from Sildigra 250, please contact your healthcare provider immediately. You can refer to the comprehensive list of side effects associated with medications containing sildenafil: Full List of Side Effects for Medications Containing Sildenafil.

The side effects outlined below require immediate medical attention.

  • Uncommon side effects:

    • Lightheadedness.
    • Tenderness in the stomach area.
    • Urine that is cloudy or bloody.
    • Priapism (painful erections)
    • More frequent need to urinate.
    • Painful urination.
    • Burning or aching in the bladder.
    • Prickling, tingling, or numbness sensations.
    • A feeling of burning or discomfort in the chest or abdomen.
    • Nausea.
  • Rare side effects:

    • Seizures.
    • Changes in vision.
    • Unusual weakness or fatigue.
    • Stress or nervousness.
    • Blurred vision.
    • Heightened thirst.
    • Difficulty focusing.
    • Expansion of the pupil.
    • Feeling of something in the eye.
    • Fever or chills.
    • Unusual sensation of burning or stinging on the skin.
    • Restless sleep.
    • Severe or persistent headache.

Less significant side effects

  • The side effects most commonly discussed:

    • Sneezing.
    • Flushing.
    • Headaches.
    • Nasal congestion or runny nose.
    • Muscular aches and pains.
    • Nasal bleeding.
    • Diarrhea.
    • Discomfort and tenderness around the eyes and cheekbones.
    • Insomnia.
  • Infrequent side effects:

    • Coughing.
    • Swallowing difficulty.
    • Enlargement of the face, hands, feet, or lower legs.
    • Tinnitus.
    • Asthma worsening.
    • Poor coordination.
    • Ulcers in the mouth or on the lips.
    • Vomiting.
    • Difficulty breathing.
    • Diarrhea or cramps (severe or ongoing).

Related Products


  • Sildenafil: MedlinePlus Drug Information. Available online: Reference Link
  • Sildenafil Interactions: Available online: Reference Link
  • Sildenafil (Oral Route) Side Effects: Available online: Reference Link
  • Definition & Facts for Erectile Dysfunction: Available online: Reference Link


MedzPills is dedicated to providing visitors with accurate and reliable health information. This article has been carefully reviewed by an expert, Parry Stone. However, it’s important to understand that this information is not a substitute for advice from a qualified medical professional. Our information is meant to be a helpful resource, but it might not cover every aspect of health conditions, lab tests, medications, potential side effects, drug interactions, warnings, or alerts. It’s strongly recommended that you consult your doctor for any specific questions or concerns about a particular illness or medication. At MedzPills, our goal is to complement, rather than replace, the important doctor-patient relationship.


Active Ingredient

Sildenafil Citrate


Erectile Dysfunction


RSM Enterprises



Equivalent Brand



10 tablets in 1 strip

Delivery Time:

6 To 15 days


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